Iwaniec, UT, Boghossian, S, Lapke, PD, Turner, RT , Kalra, SP (2007) Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice. Peptides, 28:1012-1019 Miner, JN, Chang, W, Chapman, MS, Finn, PD, Hong, MH, Lopez, FJ, Marschke, KB, Rosen, J, Schrader, W, Turner R, van Oeveren, A, Viveros, H, Zhi, L, Negro-Vilar, A (2007) An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate. Endocrinology, 148:363-73 Shogren, KL, Turner, RT , Yaszemski, MJ, Maran, A (2007) Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death in osteosarcoma cells. Journal of Bone Mineral Research, 22:29-36 Sibonga, JD, Iwaniec, UT, Shogren, KL, Rosen, CL, Turner, RT (2007) Effects of parathyroid hormone (1-34) on tibia in an adult rat model for chronic alcohol abuse. Bone, 40:1013-1020 Trevisiol, CH, Turner, RT , Pfaff, JE, Hunter, JC, Menagh, PJ, Hardin, K, Ho, E, Iwaniec, UT (2007) Impaired Osteoinduction in a Rat Model for Chronic Alcohol Abuse. Bone, 41(2):175-180

Additional OSU HHS Author(s): Hardin, Karin    Ho, Emily   

Turner, RT , Evans, GL, Lotinun, S, Lapke, PD, Iwaniec, UT, Morey- Holton, E (2007) Dose response effect of parathyroid hormone on cancellous bone in hindlimb unloaded rats. Journal of Bone and Mineral Research, 22(1):64-71

Bliziotes, M, Sibonga, JD, Turner, RT , Orwoll, E (2006) Periosteal Remodeling At The Femoral Neck In Non-Human Primates. Journal of Bone and Mineral Research, 21:1060-1067 Borah, B, Dufresne, TE, Ritman, EL, Jorgensen, SM, Liu, S, Chmielewski, PA, Phipps, RJ, Zhou, X, Sibonga, JD, Turner, RT (2006) Long-term Risedronate Treatment Normalizes Mineralization and Continues to Preserve Trabecular Architecture: Sequential Triple Biopsy Studies with Micro-Computed Tomography. Bone, 39:345-352 Chiccoa, AJ, McCarty, H, Reed, AH, Story, RR, Westerlind, KC, Turner, RT, Hayward, R (2006) Resistance Exercise Training Attenuates Alcohol-Induced Cardiac Oxidative Stress. European Journal of Cardiovascular Prevention Rehabilitation, 13:74-79 Maran, A, Gorny, G, Oursler, MJ, Zhang, M, Shogren, KL, Yaszemski, MJ, Turner, RT (2006) 2-Methoxyestradiol Inhibits Differentiation and Is Cytotoxic to Osteoclasts. Journal of Cellular Biochemisty, 99:425-3 Maran, A, Shogren, K, Zhang, M, Spelsberg, TC, Kloosterboer, HJ, Turner, RT (2006) Stable Transfection of Human Fetal Osteoblast Cells with Estrogen Receptor Confers Regulation of Bone Matrix Gene Expression By Estrogenic Metabolites of Tibolone. Bone, 39:523-529 Turner, RT, Lotinun, S, Hefferan, T, Morey-Holton, ER (2006) Disuse in Adult Male Rats Attenuates the Bone Anabolic Response to a Therapeutic Dose of Parathyroid Hormone. Journal of Applied Physiology, 101:881-886

Bemis, K, Dow, E, Maran, A, Halladay, DL, Chandraskhar, S, Frolik, C, Lin, X, Li, Q, Ishra, S, Onyia, JE, Gelbert, L, Zhang, M, Sato, M, Bryant, H, Turner, R. (2005). Gene expression analysis by DNA microarray reveals novel clues to the mechanism of the catabolic and anabolic actions of PTH in bone. Journal of Cellular Biochemistry, 95:403-418 Borah, B, Ritman, EL, Dufresne, TE, Jorgensen, SM, Liu, S, Sacha, J, Phipps, RJ, Turner, R. (2005). The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: correlation to histomorphometric indices of turnover. Bone, 37:1-9, 2005 Nakai, M, Cook, L, Pyter, LM, Black, M, Sibonga, J, Turner, R, Jeffery, EH, Bahr, JM. (2005). Dietary soy proteins have no significant effect on bone and a potentially negative effect on the uterus of sexually mature Intact Sprague-Dawley rats. Menopause 12:291-298 Sibonga, JD, Turner, R. (2005). Evidence that the Cells Responsible for Bone Marrow Fibrosis in a Rat Model for Hyperparathyroidism Are Preosteoblasts. Endocrinology 146, in press. Sibonga, JD, Turner, R. (2005). Evidence that the cells responsible for marrow fibrosis in a rat model for hyperparathyroidism (HPT) are preosteoblasts. Endocrinology, 146:4074-4081 Smith, BJ, Lucas, EA, Turner, R, Evans, GL, Lerner, MR, Brackett, DJ, Stoecker, BJ, Arjamandi, BH. (2005). Vitamin E provides protection for bone in mature hindlimb unloaded male rats. Calcified Tissue International, 76:272-279 Vingren, JL, Koziris, LP, Gordon, SE, Kraemer, WJ, Turner, RT, Westerlind, KC (2005) Effect of Chronic Alcohol Intake and Resistance Training on the Skeletal-Muscle Androgen Receptor Content in Rats. Medical Science in Sports and Exercise, 37:1842-1848

Turner, R, Principal Investigator, Iwaniec, U, Lotinun, S, Ho, H, Co-Investigators (2006-2011) Etiology and Treatment of Parathyroid Bone Disease, National Institutes of Health. $188,000

Additional OSU HHS Faculty: Ho, Emily    

Manore, MM, Widrick, J, Iwaniec, U, Turner, R (2006-2010) Multidisciplinary Training in Nutrition and Physical Activity. U.S. Department of Agriculture National Needs Graduate Fellowship Grant. $229,500

Additional OSU HHS Faculty: Manore, Melinda    

Iwaniec, U, Turner, R, Co-Principal Investigators (2006-2007) Release Kinetics, BioMimetic Therapeutic Inc., PDGF. $34,675 Iwaniec, U, Turner, R, Co-Principal Investigators (2007) The Efficacy of Hops Extract in Reducing Bone Loss In Ovariectomized Rats, Pharmachem Laboratories. $35,925 Iwaniec, U, Turner, R. Central Leptin Gene Therapy to Reduce Breast Cancer Risk Factors. Department of Defense Breast Cancer Research Program Concept Award. Principal Investigator: U.T. Iwaniec, Co-Investigator: R.T. Turner, $75,000, 2004-2005. Iwaniec, UT, Principal Investigator, Turner, RT, Co-Investigator (2006) Effects of Central leptin Gene Therapy on Weight Reduction and Cancellous Bone Mass in Female Rats, College of Health and Human Sciences Grant Program, Oregon State University. $15,000 Iwaniec, UT, Principal Investigator, Turner, RT, Co-Investigator (2006-2007) GEMOS2 PDGF+Matrix, BioMeimetic Therapeutics, Inc. $59,020 Turner, R, Principal Investigator (2002-2007) Dose response effects of alcohol on bone metabolism, NIAAA. $225,000 Turner, R, Principal Investigator (2005-2006) Pharmacological Intervention to Prevent Disuse Osteopenia. $172,393 Turner, R, Principal Investigator Lotinun, S (2005-2008) Alcohol-Impaired Bone Healing: Mechanisms and Countermeasures, Department of Defense. $887,452 Turner, R, Principal Investigator, Iwaniec, U, Co-Investigator (2005- 2008) Dose Response Effects of Alcohol, National Institutes of Health. $101,000/year Turner, R, Principal Investigator, Iwaniec, U Co-Investigator (2007-2008) Role of a TGF-beta Regulated Gene in Human and Mouse Osteoblasts and Skeleton, National Institutes of Health. $30,337/year Turner, R, Principal Investigator, Iwaniec, U, Co-Investigator (2004-2009) Alcohol-impaired Bone Healing: Mechanisms and Countermeasures, Department Of Defense. $320,633/year Turner, R. Alcohol-Impaired Bone Healing: Mechanisms and Countermeasures. Principal Investigator - R Turner. This proposal will investigate the hypothesis that alcohol abuse impairs bone healing. Department of Defense, $887,452, 2005-2008. Turner, R. Dose response effects of alcohol on bone metabolism. Principal Investigator. NIAAA - $225,000/year. The goal of this project is to test the hypothesis that alcohol-induced osteoporosis is largely due to decreased IGF-1 expression by osteoblasts and that it can be prevented or reversed by treatment with PTH, 2002-2007. Turner, R. Etiology and Treatment of parathyroid Bone Disease. Principal Investigator - R Turner. NIH - $188,000/year. The goal of this project is to understand the cellular and molecular mechanisms mediating the detrimental skeletal effects of chronic hyperparathyroidism and identify therapeutic targets of intervention, 2005-2006. Turner, R. Genetic Regulation of IGF-I in Peak Bone Density of Mice. NIH - $22,000/year. Dr. Turner is a co-investigator with 0% effort on this grant. Histomorphometric analyses will be performed on the various congenic strains and sublines. This work will be performed on the proximal tibia of congenics and controls, 2001-2005. Turner, R. Pharmacological Intervention to Prevent Disuse Osteopenia. Principal Investigator. The goal of this project is to understand the cellular and molecular mechanisms associated with estrogen on bone. NASA - $172,393, 2005-2006. Turner, R. Role of a TGF-ß Regulated Gene in Human Osteoblasts. Consultant. NIDCR - $202,500/year. The general hypothesis of this project is that TIEG serves a critical role in the TGF-ß signaling pathways possibly involving the Smad proteins, 2001-2006. Turner, R. The Effects of Estrogen Metabolites on Rat Bone. Principal Investigator - R Turner. NIAMS - $181,002. The proposed research will characterize the skeletal effects of 2-OHE1 and 16a-OHE1, verify their putative tissue and gene selective actions and identify probable cellular mechanisms of action, 1999-2004.